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The most abundant conformer aqI, that was predicted for aqueous solutions, is stabilized by the hydrogen bond interactions between Ltyrosine's carbonyl group with both the Ltryptophan and Lalanine amide groups, which causes the backbone to take a planar semicircular shape
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Consistent with this, it has been observed that htt associates with HAP1
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[DOI] [PubMed] [Google Scholar] 50.Said T.M., Grunewald S., Paasch U., Rasch M., Agarwal A., Glander H.J
