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Unlike semaglutide, which targets only GLP-1 receptors, tirzepatide is a dual agonist that activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

Cellular studies of the inhibitory capacity of CLR01 in two different models suggested that the molecular tweezer could reduce the toxicity of endogenously expressed and aggregated -Syn and decrease the administrations toxic effect of exogenous -Syn oligomers, increasing the cell viability [306]
