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We have shown previously that sirtuins SIRT1 and SIRT3 have anti-fibrotic function, and their decreased tissue expression observed in skin biopsies from SSc patients, might directly contribute to the persistence of fibrosis 28,29

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Pharmacists who have completed the required training can issue (under the Holidays Act Amendment 2016) medical certificates for minor ailments (i.e., cough and cold) for eligible patients

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