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Hence, by targeting the enzymatic activity of SARM1, inhibitors may effectively prevent the depletion of NAD + , thereby maintaining cellular energy homeostasis and enhancing neuronal resilience, potentially expanding the treatment landscape for various neurological conditions

doi: 10.1182/bloodadvances.2024013212 79 Carretero-IglesiaLHallOJBerretJPaisDEstoppeyCChimenMet al