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Although a recent study has provided insights into the impact of lysine restriction on its catabolic pathways, affecting antitumor immunity 23 , and another study has found that lysine restriction inhibits the lysosome pathway and mitochondrial oxidative phosphorylation in adipocytes 33 , the complex relationship between lysine and lysosomal function in GBM cells remains poorly understood

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In the PIVENS trial, vitamin E (-tocopherol) was found to reduce MDA levels and improve histological features in MASLD patients [141]

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