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Discussion In summary, our findings uncover a previously unknown link between the ER resident and UPR sensor protein IRE1 and ferroptosis regulation independent of UPR activation and IRE1s canonical downstream effector XBP1

(2023) 2:EVIDoa2300046

As such, gadolinium-based contrast agents allow radiologists to have clearer image contrast and boost their diagnostic accuracy in some conditions, such as inflammatory and infectious diseases of the brain, bone, and spine

Each unit equals 0.01ml

This metabolic checkpoint thus acts as a protective mechanism against ferroptosis by lowering the supply of oxidizable lipid substrates