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The American Journal of Medicine

BMJ 316 : 894898 Horton TM, Blaney SM, Langevin A-M, Kuhn J, Kamen B, Berg SL, Bernstein M, Weitman S (2005) Phase I trial and pharmacokinetic study of raltitrexed in children with recurrent or refractory leukemia: a pediatric oncology group study

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Iron overload Iron overload is known to cause oxidative stress through the formation of ROS, which can damage molecular components such as lipids, DNA, and proteins
