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The direct intranasal drug delivery approach to therapeutics holds great promise for the treatment of central nervous system (CNS) disorders, as this route is non-invasive, bypasses the BBB, enhances the bioavailability, facilitates drug dose reduction, and reduces adverse systemic effects

Individuals with Parkinsons have low dopamine production in the substantia nigra

Protein loads respectively contain no EDTA/DTT, 100 mM EDTA, and 10 mM DTT

Creagan et al

Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of PI3K/Akt signaling pathway