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T., Guerreiro, J
Studies suggest that this selective engagement is associated with anti-apoptotic signaling in stressed or damaged tissues without triggering erythropoietic responses
The Lewy body formation and neuronal damage altogether enhance neurodegeneration
Subsequently, peripheral inflammation may be transmitted to the central nervous system through disruption of the blood-brain barrier and vagal nerve pathways, activating glial cells and initiating neuroinflammation

Metabolomic evidence for peroxisomal dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome