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Biochim Biophys Acta Gen Subj 2011;1810:61219

Mol Cell Biochem 435:149162 Yang Y, Bai T, Yao YL et al (2016) Upregulation of SIRT1-AMPK by thymoquinone in hepatic stellate cells ameliorates liver injury
When Ca 2+ binds to calmodulin, the protein undergoes a conformational change that enables it to interact with a wide range of target proteins in the cell, altering their activities ( Figure 1625 )

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Results vary between individuals