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Pierre et al., 2002)

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Black Box Warning (May 2017): RISK OF TOE / LOWER LIMB AMPUTATION Notes: Canagliflozin underwent a post-marketing CANVAS cardiovascular outcomes trial (the Canagliflozin Cardiovascular Assessment Study) that ended in 2017 (Karagiannis et al, 2017

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Our findings provide important insights into how cannabis use may alter biological processes

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they cross the blood-brain barrier, altering neurotransmitter balance and contributing significantly to the sensation of "brain fog" and central nervous system fatigue

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These findings remain preliminary but suggest avenues for future investigation

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