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Sibutramine, a popular antiobesity drug used worldwide since 1997, was withdrawn from the European and US markets in 2010 because of safety concerns [27,28]

2010 Dec;12(6):448-57

Weight Loss and Obesity Treatment In addition to their role in managing type 2 diabetes, GLP-1 agonists have gained significant attention for their potential in promoting weight loss and treating obesity

Lequeux, I., Ducasse, E., Jouenne, T., and Thebault, P., Eur

It inserts into the membrane, disrupts its integrity, and triggers the release of cytochrome c and other pro-apoptotic factors
