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This inflammation involves the activation of various immune cells and the release of inflammatory mediators, which contribute to the characteristic features of the disease

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T cytotoxic-1 cd8+ T cells are effector cells against pneumocystis in mice

[121] Age is also a contributing factor: elderly individuals are often achlorhydric due to reduced parietal cell function in the stomach, increasing their risk of vitamin B 12 deficiency

doi: 10.1016/j.canlet.2008.12.011
