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10.1016/j.mad.2020.111215 16 ChenL.-Y.WangY.TerkeltaubR.Liu-BryanR

TABLE 1 Small molecule ferroptosis inhibitors

Elevated SUA activates endothelial NF-B signaling, upregulating monocyte chemoattractant protein-1 (MCP-1) and intercellular adhesion molecule-1 (ICAM-1) expressions to accelerate atherosclerosis progression ( This metabolic disturbance demonstrates bidirectional interactions with components of metabolic syndrome

Although the clinical relevance of anti-PDXP has not yet been established, the recurrent identification of PLP-related enzymes as autoantigens suggests a potential role of vitamin B6 homeostasis in cancer-associated autoimmunity (Be et al

NF-B, by inhibiting ROS formation and consistently activating the JNK cascade, participates in survival signaling, effectively counteracting programmed cell death induced by the TNF- family of receptors (47)