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doi: 10.1016/S1471-4906(02)02302-5 51 ArnoldJNMagieraLKramanMFearonDT
Despite the development of numerous drugs targeting specific pathological features of AD, such as amyloid-beta (A) deposition and neurofibrillary tangles, very few have been approved in the past 20 years, underscoring the limitations of single-target therapeutic approaches
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