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One study, which also evaluated cognitive function in patients with high MMA concentrations, found no significant effects on the MDD inventory score, but only 30 of the 140 subjects had depression at baseline, which may have diluted any benefits

Development was ultimately discontinued after clinical results did not demonstrate sufficient efficacy to meet pharmaceutical thresholds

This helps researchers move from compound-specific review into broader pathway comparison without leaving the core research archive

Improved cognitive function: Vitamin plays a crucial role in maintaining healthy nerve cells and supporting brain function, which can enhance cognitive abilities such as memory and concentration