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10.1038/nature11249 Nature 93 YeeD.LeeA
EDC reacts with the carboxylic acid in iodo- or bromoacetic acid to form a reactive ester, which can react with primary amine groups on the support
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About a third, 33%, met the diagnostic criteria for nonalcoholic steatohepatitis (NASH), a more severe subpopulation of NAFLD
Reduced NO bioavailability induces LSEC capillarization characterized by loss of the LSEC window pore and basement membrane formation and leads to an imbalance in its secretion of vasoactive substances, which contributes to MASLD progression
