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This suggests that AOD-9604 does not produce weight loss in a dose-dependent manner, a unique characteristic that deviates from the norm for many other drugs

Beyond weight loss, early exploratory data suggest potential benefits including: Reductions in HbA1c (a marker of blood sugar control) in people with type 2 diabetes Improvements in lipid profiles (cholesterol and triglycerides) Reductions in liver fat, which may be relevant for metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD), though these findings are preliminary Possible cardiovascular benefits

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When any component fails, oral supplementation becomes far less effective, potentially requiring massive doses to achieve therapeutic blood levels

doi: 10.1038/309163a0