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This allows the FDA to approve drugs quickly by relying on a surrogate endpoint, which the agency describes as a marker, such as a laboratory measurement, radiographic image, physical sign or other measure that is thought to predict clinical benefit, but is not itself a measure of clinical benefit. In clearing drugs for accelerated approval, the FDA takes a risk that promising early signals seen in drug studies, such as an ability to keep tumors from growing, will eventually pay off by resulting in a clinical benefit improving or extending patients lives