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But they are not backed by the randomized controlled trials that FDA-approved products have undergone

10.1016/S0891-5849(03)00428-3 64 HuangJ.LinD.WeiZ.LiQ.ZhengJ.ZhengQ.et al (2020)
Double-enkephalinsSynthesis, activity on guinea-pig ileum, and analgesic effect

Evoking picomolar binding in RNA by a single phosphorodithioate linkage
