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Some immediate improvements may be visible, but final results may take 36 months to fully materialize

10.1016/j.jad.2010.03.003 110 ZhangX.ZhangZ.ShaW.XieC.XiG.ZhouH.et al (2009)

The loss of collagen leads to fine lines, wrinkles, and saggy skin, making people look older than they are

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