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Oxidative stress in pulmonary fibrosis is associated mainly with the NF-B signaling pathway, the Kelch-like ECH-associated protein 1 (Keap1)/Nrf2/ARE pathway, and the NADPH oxidase (NOX)4-Nrf2 signaling cascade [155]

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In conclusion, this study demonstrated that H 2 S inhibits endogenous SO 2 generation by inactivating AAT through the sulfhydration of AAT1/2 (Zhang D