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They showed an increase in the production of cytokines in peripheral blood mononuclear cells (PBMCs), and these patients (most notably those with diarrhea) showed basal levels of elevated serum TNF-, IL-1, and IL-6 [4]

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MR decreased plasma leptin and increased adiponectin were found in Fischer 344 rats feeding an-MR diet

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To estimate the bioavailability of each metal a number of methodologies have been used including chemical probes, genetically encoded probes, and measurements of the metal affinities of cognate metal sensors [57,210]