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For example, overexpression of GSH in ragged red fibers is believed to represent an attempt to counterbalance the oxidative stress of KearnsSayre syndrome [141], a mitochondrial disorder involving the central nervous system [142,143]

Hinton, T

Though human research is still emerging, its mechanism of action is promising for metabolic conditions, obesity, and possibly age-related fatigue

These compared neurometabolites between 370 patients and 342 controls, including n-acetlyaspartate (NAA), total creatine, total choline (tCho), myo-inositol, glutamate, glutamate+glutamine, GABA, and lactate

Physicians typically trial one stimulant class before switching to the other when initial therapy fails to achieve an adequate clinical response