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Interestingly, it can take years for B12 stores to deplete to a point where a deficiency becomes apparent: Vitamin B12 deficiency affects multiple systems, and sequelae vary in severity from mild fatigue to severe neurologic impairment
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Adaptive resistance to MAPK inhibition in colorectal cancer
doi: 10.1016/j.jneuroim.2021.577600 [DOI] [PubMed] [Google Scholar] 68
This study compared the efficacy of a treatment regimen combining tetracycline, nicotinamide, and topical steroids with prednisone monotherapy
