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For pH of cultures, 250 L of bacterial cultures at indicated time points were taken and spun down at 12,000 rpm for 10 min to pellet down bacterial cells

69 These deficiencies are owed to defects, which comprise malabsorption, smoking, alcohol abuse, and improper diets

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When used in combination with other medical treatments, melatonin has been shown to enhance the overall effectiveness of melasma therapies by reducing oxidative stress and inhibiting melanin production

Furthermore, levels of pro-inflammatory mediators such as interleukin-1, interleukin-1, interleukin-6, interleukin-8, interleukin-17, interleukin-27, nitric oxide, inducible nitric oxide synthase, C-X-C motif chemokine ligand 8, C-C motif chemokine ligand 2, cyclooxygenase 2, granulocyte colony-stimulating factor, and monocyte chemotactic protein-1 can be decreased by curcumin (Laurindo et al., 2023