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Based on the evidence emerging from the recent trials showing that NAC can reduce exacerbations in patients with COPD, including those taking ICS, the 2020 Global Initiative for Chronic Obstructive Lung Disease (GOLD) report includes NAC, as well as other thiol-based drugs, as additional therapies to consider in the treatment of COPD [33]

These crustacean-specific genes are divided into two distinct clades within the lipocalin protein superfamily
Similar findings have been reported in mice, where AX inhibited the increase in liver TG levels induced by high-lipid diets (Ikeuchi et al., 2007)

Glutathione and NAC are also fairly exceptional due to their thiol group, which contains sulfur