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In the early stages, apoptosis is marked by cell shrinkage, chromatin pyknosis (condensation), a reduction in cell volume and an increase in cytoplasmic density, along with more compact organelles (101,104)

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Due to the fact that these conditions will fluctuate in response to the arduous demands of two years of breastfeeding and nine months of pregnancy, there is cause for concern regarding the nutritional status of pregnant women during gestation