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Tirzepatide for MASH with fibrosis 15 mg produced a large majority disease-resolution rate versus a small placebo rate: Loomba NEJM 2024 (SYNERGY-NASH)

En prvention ou en entretien , une supplmentation rgulire (quotidienne ou hebdomadaire) peut suffire, parfois de manire prolonge, notamment chez les personnes ne consommant pas ou peu de produits animaux (vgtariens, vgtaliens)

Diets with low levels of protein and iron can also result in low vitamin B12 levels

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Be aware that sublingual B-12 supplements often contain sugar substitutes such as sorbitol, mannitol or sucralose, which can cause gastrointestinal symptoms in some people
