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They also improve the ratio of active to oxidized glutathione

T., Dillner, K., Wu, X., Pousette, A., Norstedt, G

Tolerance to high temperature stress in plants is often associated with an increase in antioxidant enzyme activities 41

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Blockage of Bcl-XL function by PUMA- gives way to Bax and Bak to change their conformation and form pores in the outer mitochondrial membrane, leading to the cytochrome c release into cytosol, apoptosome formation, subsequent caspase activation, and following apoptosis [33, 34]
