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Clarifying these molecular underpinnings is therefore essential for establishing mechanistic bridges between cellular dysfunction and systemic disease features, and for identifying precise molecular targets for therapeutic intervention

Melatonin signal transduction pathways require e-box-mediated transcription of Per1 and Per2 to reset the SCN clock at dusk

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doi: 10.3748/wjg.v26.i10.1020 63 LiuZ.HuangH.ZengY.ChenY.XuC
