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Beneficial effects of pioglitazone, a selective peroxisome proliferator-activated receptor- agonist in prenatal valproic acid-induced behavioral and biochemical autistic like features in Wistar rats

Moreover, inhibition of xanthine oxidase increases the levels of hypoxanthine and xanthine, which in turn inhibit de novo purine biosynthesis via a feedback mechanism, an essential treatment pathway for some of the antineoplastic drugs (Rahaman et al., 2022)

Moreover, GRX act in antioxidant defence by reducing dehydroascorbate, peroxiredoxins, and methionine sulfoxide reductase

Biol Psychiatry (2010) 67:10106.10.1016/j.biopsych.2009.12.004 256 McCullumsmithREKristiansenLVBeneytoMScarrEDeanBMeador-WoodruffJH
Recent studies have demonstrated that DHODH plays a significant role in the prevention of ferroptosis by eliminating mitochondrial lipid peroxides through the scavenging of free radicals with the assistance of CoQH2 [30]
