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Interestingly, SAPs hydrogels can also safely encapsulate cells or drugs for specific therapies (Zhan et al., 2013
Since ROS can reduce NO availability, this positive feedback modulation of ROS may largely increase ROS production and strongly suppress NO generation, which may overcome the vasodilation effect of hyperpolarization, and therefor predominantly facilitate vasoconstriction
Kojima K, McQueen T, Shpall E, R-Y W, Andreeff M
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J Biol Chem 289: 1159211600, 2014
