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ROS can also activate the mitogen-activated protein kinase (MAPK) signaling pathway and activator protein-1 (AP-1), thereby the upregulating matrix metalloproteinases (MMPs) and degrading matrix collagen [24]
[PubMed: 7299290] 700
Yang K, Wang X, Song C, He Z, Wang R, Xu Y, et al
[DOI] [PubMed] [Google Scholar] 54.McBride R., van Zyl M., Fielding B.C
A secondary analysis of the CTN X: BOT trial
