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All authors have read and agreed to the published version of the manuscript

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6 The reason for mitochondrial dysfunction in ASD is unknown, but the fact that only 23% of children with ASD and MD have a known mitochondrial deoxyribonucleic acid (mtDNA) abnormality suggests that MD may be acquired rather than genetic in many ASD cases

Others here have found no alterations in energy metabolism when individuals with cirrhosis of the liver were given LC, but they did find increases in exercise tolerance, which suggests good energy metabolism

Glycine can also improve cognition through anti-excitatory effects, [31-33] and stimulation of the N-methyl-D-aspartate (NMDA) receptors , [34,35] which supports a process called long-term potentiation (LTP)