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Bruxism significantly elevates the risk of developing TMD, increasing the odds by 2.25 times overall, with awake bruxism increasing the risk by 2.51 times and sleep bruxism by 2.06 times (20)

On a cellular level, coenzyme Q10 (CoQ10) is necessary for the production of energy within the mitochondria

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Fertility issues are uncommon, although women are advised to avoid pregnancy for 612 months and men to avoid conception for at least 6 months post-treatment
