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Subsequently, bivalent ferritin is deproteinized via divalent metal-ion transporter-1 or metal transporter ZIP14 (Slc39a14) to form Fe 2+ and enters the labile iron pool

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In the future, the development of lateral flow assay technology for detection of heavy metal ions will focus on multiplex detection, optimization of signal amplification strategies, integration with portable devices, and standardization and commercialization

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