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[DOI] [PMC free article] [PubMed] [Google Scholar] Tarnawski AS, Ahluwalia A

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In fact, NO at high levels inhibits heme insertion in hemoglobin, NO synthases, and heme thiolate enzymes, such as cytochrome P450s (CYP) in different manners (i.e., through the direct binding to the heme iron or to covalent modications in Pharmaceuticals 2025,18, 185 12 of 21 heme transfer proteins) [ 147 149 ]

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This peptide has been studied for its potential role in supporting tissue repair and recovery processes throughout the body