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Simulation of DORs modulates the activity of mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK), subsequently impacting cell function, survival, and synaptic plasticity [50]

Investigation of the mechanism of this action uncovered the potential of Epithalon to interact with the promoter region of the interferon-gamma gene

Lifespan Data (Primary Efficacy Signals): CBA Mice: Treatment with Epitalon extended Maximum Lifespan by 11.9% (oldest survivor 34 months vs

Epitalon produces antioxidant effects in the body by activating antioxidant enzymes, such as glutathione peroxidase

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