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Venable ME, Webb-Froehlich LM, Sloan EF, Thomley JE

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The National Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs) in the UK, for instance, encourages researchers to reduce the use of animals or animal-derived products in scientific research (Poh and Stanslas, 2024)

We found that inhibiting SLC7A11 expression significantly enhanced the efficacy of APR-246, particularly against cancer cells with mut-p53 accumulation (Fig