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The presence of funnel plot asymmetry also suggests potential publication bias, which warrants further scrutiny

First, the complex appears to act as a copper transporter, delivering ionic copper to cutaneous cells where it may activate copper-dependent enzymes involved in extracellular-matrix remodeling and angiogenesis

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For MMUT to function properly, a third protein, MMAA, is required to protect MMUT against oxidative stress and to reactivate the enzyme [107]