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The activity of MMPs is tightly regulated by tissue inhibitors of metalloproteinase (TIMPs)

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Other reactions of the PPP that are of less physiological significance are designed to convert dietary five carbon sugars into both six (fructose-6-phosphate) and three (glyceraldehyde-3-phosphate) carbon sugars which can then be utilized by the pathways of glycolysis

In hypertensive renal injury, it was demonstrated that SIRT7 has a potential protective role in alleviating ferroptosis and lipid peroxidation through the Krppel factor 15/ nuclear factor 2 (KLF15/Nrf2) signaling pathway (Li et al