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5-Amino-1MQ works by inhibiting NNMT, the enzyme that methylates nicotinamide (a precursor to NAD+) and sends it toward excretion rather than recycling into energy pathways

Vitamin B12 is an essential nutrient involved in red blood cell formation, neurological function, DNA synthesis, and cellular energy metabolism

Quick Answer: Tirzepatide has no established direct effect on vitamin B12 levels, but indirect factors such as reduced dietary intake, slowed gastric emptying, and concurrent metformin use may increase deficiency risk

Weeks 8-12+: More substantial changes for those who persist

its deficiency causes anemia, fatigue, and weakness