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[DOI] [PubMed] [Google Scholar] 244.Lee JY, Choo JE, Choi YS, Shim IK, Lee SJ, Seol YJ, et al

Plain-English take: Epitalons strongest, most direct evidence is mechanistic (telomerase/telomeres, redox biology) and circadian (melatonin) with early human signalsmainly via the parent pineal extractsuggesting better sleep architecture, cardio-metabolic markers, and immune tone in aging populations

These include water retention, joint discomfort, or changes in blood sugar regulation