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In brief, the synovial tissues were collected, washed with PBS, chopped with scissors, and soaked in PBS mix with type I collagenase (4 mg/mL) in cell culture incubators for 3 h

However, an earlier review reported no improvement in reaction time, immediate memory or delayed recall in young adults with cognitive impairment

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doi: 10.1016/0009-8981(93)90138-t
