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Shorb knew that the same liver extract was used to treat pernicious anemia (her father-in-law had died from the disease), and concluded that LLD could be developed as an assay method to identify the active compound

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They help health and social care professionals to prevent ill health, promote good health and improve the quality of care and services

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Furthermore, a negative association of IGF-1 with CC-IMT was observed only in patients with low vitamin D levels (152) and was supported by findings of a comparative study of obese individuals and healthy controls showing that IGF-1 protects against CC-IMT when serum vitamin D levels are low (154)