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Description
In addition, Hsp70 promotes the multimerization of LAMP type 2a, the lysosomal receptor involved in CMA, to form a translocation complex 49,50 , in which a translocation channel is further formed 51 through which only unfolded substrates are permitted to pass 52
doi: 10.1016/j.nano.2019.102117 2
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Despite the controversy, IF may enhance cardiometabolic health by promoting circulating HDL levels
Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress
