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At endpoint A, the gene encoding NFIC is upregulated in the SEV group compared to controls (contrast 2), suggesting an important role for this TF in the transcription of inflammatory genes in severe COVID-19

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As part of immunotherapy, tumor cells may undergo enhanced lipid peroxidation through ferroptosis induced by activated CD8+ effector T cells (134)

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Nrf2/Keap1/ARE signaling: towards specific regulation
