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Protein programmed death 1 (PD-1) PD-1 and its related ligand PD-L1 are one of the major pathways that negatively regulates the activity of immune system

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[DOI] [PubMed] [Google Scholar] 121.Ushiyama M., Morita T., Kuramochi T., Yagi S., Katayama S
Disturbed balance between Th1 and Th2 can lead to long-lasting health consequences since the window between beneficial and damaging levels is very narrow