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doi: 10.1111/cea.14112

23 Furthermore, it was shown that vitamin C can play a role as a carcinostatic agent by inhibiting angiogenesis via decreasing the expression of angiogenesisrelated genes such as basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and matrix metallopeptidase 2 (MMP2)

doi: 10.1016/j.tplants.2016.08.002 18 Di MeoSReedTTVendittiPVictorVM

Additionally, the histone glycosylation mediated by O-linked N-acetylglucosamine transferase (OGT) is the driver of DTP generation, and OGT catalyzes the addition of monocyclic O-GlcNAc subunit to serine or threonine residues of histones [100]

Given the strong associations between heart aging traits and the heart age gap, we used longitudinal follow-up among healthy participants in the LonGenity cohort to test if organ age was significantly associated with future heart failure risk (Fig
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